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By AI, Created 4:27 PM UTC, May 18, 2026, /AGP/ – Headache specialist Egilius L.H. Spierings says new MRI and biomarker research may help migraine science, but doctors should not treat patient-reported symptoms as guesswork. He argues current migraine care is already effective and that the future should balance technology with clinical judgment.
Why it matters: - Migraine affects about 15% of the global population, so how doctors diagnose and treat it has wide real-world impact. - Dr. Egilius L.H. Spierings says overreliance on imaging and biomarkers can push patient experience to the side, even though symptom reports remain central to care. - The debate matters because treatment decisions shape quality of life, missed work, and long-term disease burden for millions of patients.
What happened: - Dr. Egilius L.H. Spierings, a headache-and-face-pain specialist, pushed back against claims that migraine treatment is “pretty much guesswork.” - His comments came after a Stanford Medicine study, reported by Medical Xpress, suggested functional MRI scans may help identify biological migraine subtypes and improve treatment decisions. - Dr. Spierings said the discussion is drifting too far toward brain imaging and away from listening to patients.
The details: - Dr. Spierings said many disorders are diagnosed and treated based on a patient’s symptom description, and migraine should be no different when clinicians listen carefully. - He argued that lab findings, imaging and biomarkers are gaining too much influence compared with patient-reported experience. - Dr. Spierings said patients often know what is wrong with them and physicians should analyze that information without needing biomarkers to validate it. - Migraine is commonly classified as with or without aura, and as episodic or chronic based on headache frequency. - Dr. Spierings said those categories alone should not determine whether preventive treatment is needed. - Preventive treatment depends on overall headache burden, how well abortive treatments work, and whether the patient wants prevention. - Dr. Spierings criticized older migraine treatments cited in the study, including beta-blockers and anticonvulsants, as often poorly tolerated and only modestly effective. - He identified CGRP-targeted medicines, including CGRP antibodies and gepants, as the current standard of care. - Dr. Spierings said those newer treatments are generally very well tolerated, extremely safe and highly effective. - He said medicine should not lose sight of the patient sitting in front of the doctor. - More information is available here.
Between the lines: - Dr. Spierings is not rejecting research; he is arguing against using early imaging findings to overshadow day-to-day clinical judgment. - His comments suggest a broader tension in medicine between high-tech diagnostics and bedside evaluation. - The criticism also reflects concern that calling migraine care “guesswork” could erode patient confidence in treatment that already works for many people.
What’s next: - Migraine research will likely continue exploring MRI-based subtypes and biomarkers. - Dr. Spierings expects future care to combine scientific advances with stronger attention to patient-reported symptoms and physician expertise. - He is available for interviews as the debate over migraine diagnosis and treatment continues.
Disclaimer: This article was produced by AGP Wire with the assistance of artificial intelligence based on original source content and has been refined to improve clarity, structure, and readability. This content is provided on an “as is” basis. While care has been taken in its preparation, it may contain inaccuracies or omissions, and readers should consult the original source and independently verify key information where appropriate. This content is for informational purposes only and does not constitute legal, financial, investment, or other professional advice.
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